Syrgiannes Palaiologos Philanthropenos (, 1290 – 1334) was a Byzantine aristocrat and general of mixed Cuman and Greek descent, who was involved in the civil war between Emperor Andronikos II Palaiologos (r. 1282–1328) and his grandson Andronikos III (r. 1328–1341). Loyal only to himself and his own ambitions, he switched sides several times, and ended up conquering much of Macedonia for the Serbian ruler Stefan Dušan (r. 1331–1346) before being assassinated by the Byzantines.