Juan de la Cerda, 4th Duke of Medinaceli, (c. 1514 – 1575), Grandee of Spain, was a Spanish nobleman. He was the son of Don Juan de la Cerda, 2nd Duke of Medinaceli, by second wife María de Silva. In 1552 Juan de la Cerda inherited the titles from his older half-brother Gastón de la Cerda y Portugal. In 1567 he was appointed Viceroy of Navarre supposedly staying there till 1572, but it seems that towards the end of 1570, he became head of the household of Queen Anna of Austria, position he held until his death in 1575.