The Rogue Isles is the setting of City of Villains. It is a fictional group of islands off the Atlantic Coast of the United States and the base of operations of Lord Recluse and his Arachnos organization. Geographically, the Rogue Isles are a small chain of islands NW of Bermuda that run in a band 50 to 20 miles off the US coast. Officially known as the Etoile Islands, there are dozens of islands in the chain. The main cluster of the group, home to Spider City, is at the 50 mile marker, outside U.S. jurisdiction. From there the smaller islands string toward the US coast.