Langhorne Wesley Wister (September 20, 1834 – March 19, 1891) was an American Union brevet brigadier general from Pennsylvania during the period of the American Civil War. He served as a colonel of the 150th Pennsylvania Volunteer Infantry, assuming command on the first day of the Battle of Gettysburg. He also fought at the Battle of Fredericksburg, the Battle of Chancellorsville, and in the Wilderness. He received his appointment as brevet brigadier general dated to March 13, 1865.