The 22nd Marine Regiment (22nd Marines) is an inactive United States Marine Corps infantry regiment. The 22nd Marines was activated in June 1942 during World War II. The Marine regiment was under the command of a Task Force, the 1st Provisional Marine Brigade, and the 6th Marine Division, fighting in the battles of Eniwetok, Guam, and Okinawa. The regiment served in Northern China following the war and were subsequently deactivated in March 1946. The 22nd Marines was reactivated at Marine Corps Base Quantico, Virginia in 1947 and was fully deactivated in October 1949.