Francis I de Bourbon, Count of St. Pol, Duke of Estouteville (6 October 1491 – 1 September 1545), was a French prince and important military commander during the Italian Wars. Francis was the second son of Francis, Count of Vendôme and Marie de Luxembourg, Countess of Saint-Pol. As such he was a prince du sang in France. His appanage, the countship of St. Pol, came from his mother's Luxembourg inheritance. He was present at the meeting between Francis I of France and Pope Clement VII in Marseille in 1533.