Jacob II was the Catholicos of the Armenian Apostolic Church between 1327 and 1341, and then again between 1355 and 1359. He was the nephew of a previous Catholicos, Gregory VII of Cilicia. During a Mamaluke invasion he and King Leo IV of Armenia got into a severe disagreement over how to deal with the situation. The dispute grew so large that Jacob threatened Leo with the vengeance of the church. Leo was so enraged by this that he had Jacob deposed from the pontificate. Mukhitar Ter Mukhik from the village of Curnah was elected pontiff in his place.