Brenda McFarlane is the wife of Colin McFarlane. She first appears looking for Chas Dingle, who was sleeping with her husband Colin when he died. Chas thinks that Brenda wants revenge so she and Lexi Nicholls prepare to run away. However, the following day they meet her when she turns up at Chas's house. To their surprise, Brenda hands them some money to thank them for killing her husband - although Colin died of natural causes.