Born in Los Angeles, California, Duhame is the son of stuntman and stunt coordinator Doc Duhame and the brother of stuntwoman Rachel Duhame. He started as an actor at the age of seven and performed in television series The Martin Shot Show (1994), the movie The Little CHP (1995, with Robert Pine), Jodie Foster's comedy Home for the Holidays (1995, with Angela Paton), the television series The Wayans Bros. (1996, with Paul Willson) and L.A. Firefighters (1996, with Peter Crombie and Jack Shearer), Harold Ramis' comedy Multiplicity (1996, with Harris Yulin and John de Lancie), Chicago Hope (1996, with April Grace, Scott Jaeck, and Brian Reddy), Beyond Belief: Fact or Fiction (1997), and the television comedy Toothless (1997, starring Kirstie Alley).