A Spire Missile (or more commonly simply a Spire) is a Chimeran biological weapon designed to infect large numbers of humans with the Chimeran virus. Spire missiles can wipe out entire cities in a matter of minutes, and have become one of the Chimera's most effective and lethal weapons. A Spire missile is fired from a Goliath into human-held areas. After impacting and embedding itself into the ground, the Spire opens up and releases its deadly payload of Crawlers. By Resistance 2, Spinners are the main payload of Spires.