Luigi Oreglia di Santo Stefano (July 9, 1828, Bene Vagienna, Italy – December 7, 1913, Rome, Italy) was a cardinal of the Catholic Church in the late nineteenth century. He was Bishop of Ostia and Dean of the Sacred College of Cardinals from 1896 until his death. Oreglia retained his positions with the College of Cardinals right up to his death in 1913 at the age of eighty-five.