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Imogene was born some time after her father and the Five studied at Oxford. When she fell ill, Adam approached Helen Magnus and James Watson to ask for their help. The pair eventually discovered that the girl was suffering from Leukemia, a form of cancer, and that there was little that could be done. Adam pleaded with Magnus to use her "blood experiments", but she refused due to the fact the source blood was hidden by then and that it could potentially kill a child in such a weakened state.

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