Carmine John Persico, Jr. was born on August 8, 1933, in Brooklyn, New York, to Carmine John Persico, Sr. and Assunta "Susan" Plantamura. Carmine Persico, Jr. is the brother of Colombo capos Theodore Persico and Alphonse "Allie Boy" Persico (died in 1989). Carmine Persico's sons are Colombo former Acting Boss Alphonse Persico, commonly known as "little Allie Boy" (named after Carmine's beloved older brother) and Colombo associate Michael Persico. Carmine Persico Jr.'s nephew is Theodore Persico Jr.