During an attack on New Tek City, in which Doctor Plague's goons were defeated by Chaotix, Plague refused to run away. He threatened to smash a vial containing a virus powerful enough to wipe out all life in the city. He tried to follow through on this threat when antagonized by Sonic, hurling the vial at the ground and screaming that he would be remembered as the one who destroyed New Tek City. Sonic was able to catch the vial in midair.