While better classified as a joint business venture between several criminals, the Loco Syndicate was a collective outfit dealing with drugs, primarily cocaine. The Syndicate had its main operations based in San Fierro, and was made up of San Fierro's most powerful pimp Jizzy B, gang leader T-Bone Mendez, and the mysterious businessman (later revealed to be an undercover government agent) Mike Toreno. Former Grove Street Families gang banger Big Smoke, after being lawfully protected by corrupt LSPD C.R.A.S.H officers Frank Tenpenny and Eddie Pulaski, organizes a large crack-cocaine empire, establishing a business venture with the Syndicate, sending his right-hand man, Ryder, who would become his formal representative to conduct an alliance. The Loco Syndicate was the largest organization i