The main hazard in this dungeon is Warps. Bring Null Warp monsters to move around the map and to deal damage to enemies. The Dr. Gingers has a Skull on them. Defeating them will decrease the Defense of enemies. Itsuki has a lot of HP so you need the DEF Down to defeat him. The most effective way to clear mobs is by pinching. Have Bounce monsters to quickly defeat the Dr. Gingers for the DEF Down.