Thomas Clark (August 1741 – 25 December 1792) was an American officer from North Carolina who fought in the American Revolutionary War. Born to parents Thomas Clark and Barbara Murray, he became a brother-in-law to William Hooper, signer of the United States Declaration of Independence. On 1 September 1775 he was elected Major of the 1st North Carolina Regiment. He was promoted to Lieutenant Colonel on 10 April 1776 and led the regiment at the Battle of Sullivan's Island in June of that year. Elevated in rank to colonel of the 1st North Carolina on 5 February 1777, he led the unit at Brandywine and Germantown in the late summer and fall of 1777.