The rebellion spanned the reigns of three Tang emperors before it was quashed, and involved a wide range of regional powers; besides the Tang dynasty loyalists, others involved were anti-Tang families, especially in An Lushan's base area in Hebei, and Arab, Gokturk, and Sogdian forces or influences, among others. The rebellion and subsequent disorder resulted in a huge loss of life and large-scale destruction. It significantly weakened the Tang dynasty, and led to the loss of the Western Regions.