When Herbert hops outside Chris Griffin’s window on a ladder in "Brian the Bachelor", the whole scene up to when he falls down is a parody of a scene from the film. In "Mother Tucker", Stewie Griffin intends to play a clip of "Food Fight!" from the film during a broadcast of Dingo and the Baby. He instead plays a clip from Philadelphia by mistake. When Lois tells Peter that Brian tried to have sex with her in "Play It Again, Brian", Peter asks, "Was he bigger than me?", a quote originating from Animal House.