The real skill of the assassin isn't their ability to kill their target. All Black Hand operatives are more than capable of killing another Cainite, even one of considerable age and power, if given sufficient opportunity. What sets the assassins apart from their fellows in the Hand is their ability to kill their target on his home ground (sometimes even surrounded by allies and formidable defenses), to do so quietly and efficiently, and to just as quietly depart without raising even a hint of alarm.