A basidiosac rupture was an issue that might occur while using spore drive. After the crew of the USS Glenn was lost during spore drive maneuvres in 2256, a team sent to determine the cause saw spiral etchings on its hull that provided evidence of catastrophic basidiosac rupture. Later, helical trauma correlating to these markings were found in one of the dead crew. (DIS: "Context Is for Kings")