The institution of the cardinal-nephew evolved over seven centuries, tracking developments in the history of the Papacy and the styles of individual popes. From 1566 until 1692, a cardinal-nephew held the curial office of the Superintendent of the Ecclesiastical State, known as the Cardinal Nephew, and thus the terms are sometimes used interchangeably. The curial office of the Cardinal Nephew as well as the institution of the cardinal-nephew declined as the power of the Cardinal Secretary of State increased and the temporal power of popes decreased in the 17th and 18th centuries. Notable cardinal-nephews include at least fifteen, and possibly as many as nineteen popes (Gregory IX, Alexander IV, Adrian V, Gregory XI, Boniface IX, Innocent VII, Eugene IV, Paul II, Alexander VI, Pius III, Jul
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