Plutonius is a nuclear warhead worshiped as a god by a cult of ghouls in Kansas City in 2197. It was produced by Manhattan Projects Inc.. Before the Great War, Kansas City was a major nuclear launch site. After the city was hit by the bombs, the surviving silo staff were turned into ghouls, and formed a town called Gravestone in the ruins of the city. Only one nuclear bomb was left intact in the silos, and the ghouls took to worshiping it as a god, Plutonius.