Nyoka's father Dr. John Meredith came to Africa with his daughter to escape the shame brought upon their family by his criminal twin Bradley. Dr. Meredith uses his medical skills to help the natives and ends up displacing the local witch doctor of the Masamba, Shamba. However Shamba later teams up with Bradley and Slick Latimer, who arrived looking for a local diamond mine, to kill Dr. Meredith. Bradley then replaces his brother and takes over his life. Nyoka discovers their plan teams up with Jack Stanton and Curly Rogers to stop her villainous uncle and his allies.