He was born near East Bend, North Carolina. Shore graduated from Guilford College in 1913. Along with Babe Ruth, he was sold by the Baltimore Orioles to the Red Sox. Shore's best year with the Red Sox was 1915, when he won 18, lost 8 and compiled a 1.64 earned run average. He was 3–1 in World Series action in 1915 and 1916. He missed the 1918 Red Sox World Championship season, having enlisted in the military in that war year. Shore was sold to the New York Yankees by Red Sox owner Harry Frazee, where he closed out his career. He died on September 24, 1980, aged 89.