William Edwin Baldwin (July 28, 1827 – February 19, 1864) was a Confederate Army officer during the American Civil War. A bookstore owner and member of the local militia in Columbus, Mississippi, Baldwin enlisted in the Confederate Army soon after Mississippi announced its secession from the Union, accepting a commission as Colonel of the 14th Mississippi Infantry. Stationed briefly in Pensacola, Florida, he was transferred with his unit to East Tennessee and later central Kentucky, where he fought and was later captured at the Battle of Fort Donelson.