Leonardo Patrasso (Alatri, 1230 - Lucca, 7 December 1311) was an Italian Franciscan and Cardinal. He was a canon at Alatri, and from 1290 its bishop. He was bishop of Aversa from 1297 to 1299. His nephew, Pope Boniface VIII, made him a cardinal in 1300. Dean of the Sacred College of Cardinals, August 1309 until his death.