James Orlando Harrison Simrall, Jr. (November 16, 1909 – September 8, 1982) was an American football player and medical doctor. A native of Lexington, Kentucky, Simrall enrolled at the University of Michigan where he played quarterback and halfback for the Michigan Wolverines football teams from 1928 to 1930. He was selected as the Most Valuable Player on the 1929 team and the captain of the 1930 team. He later attended Harvard Medical School, served as an instructor in obstetrics and gynecology at the University of Michigan, and later became a medical doctor in Lexington, Kentucky.