Humulin 50/50 is the US brand name for Lilly's r-DNA/GE/GM human insulin mix consisting of 50% R/neutral insulin and 50% NPH/isophane crystal insulin. It is the same as Mixtard 50, Actraphane 50/50 and Aventis' Insuman Comb 50. Lilly stopped offering this insulin, under the brand name Humulin M5, in the EU & UK in July 2004.