Pecos Pest was directed by Hanna and Barbera, and was the last Tom and Jerry cartoon released to be produced by Fred Quimby before he went into retirement. The cartoon was also the last Tom and Jerry cartoon produced in Academy format; all subsequent Tom and Jerry cartoons were released in CinemaScope format. It was animated by Ed Barge, Irven Spence, Lewis Marshall and Kenneth Muse with backgrounds by Robert Gentle. Uncle Pecos and his music were performed (uncredited) by Shug Fisher.