The Simian Flu, formerly known as ALZ-112 and ALZ-113, was an artificially created retrovirus designed to cure Alzheimer's disease. The brainchild of Dr. Will Rodman of the Gen-Sys Laboratories, the first virus proved a success with ape test subjects by greatly enhancing their intelligence, and managed to temporarily cure Rodman's own father. In order to make the effects permanent in humans, a second, more powerful and contagious strain was created which ultimately proved fatal to humans, leading to the Simian Flu Pandemic and the rise of the Evolved Apes.