Samantha Mathis is an American actress. On House, M.D. she portrayed the seemingly loving wife Maria Palko to patient Bob Palko in the Season 2 episode Clueless. Mathis has been acting professionally since the age of 16. At the age of 18, she landed a regular role on Aaron's Way and since then has had featured roles in Knightwatch, Pump up the Volume, FernGully: The Last Rainforest, Super Mario Bros., Little Women, The American President, Broken Arrow, American Psycho, Harsh Realm, First Years, The Mists of Avalon, The Punisher, Salem's Lot, Local Color, Grey's Anatomy and Good Day For It.