John Amsterdam is a brilliant NYPD homicide detective who is immortal. He is over 400 years old, but his body structure is that of a 35-year-old. Born on June 1, 1607 as Johann van der Zee, Amsterdam was a Dutch soldier in the year 1642 when he was stabbed through the heart after he stepped in front of a sword to save the life of a Native American girl during a massacre of her tribe. She and the women shaman of her Lenape village in turn rescued Amsterdam by weaving an ancient spell that conferred immortality upon him. He will not die or age until after he finds his one true love, and only then will he become whole and ready for mortality. His immortality has resulted in Amsterdam spending more than three centuries marked by loss as his friends, lovers, children (63), and dogs (which John
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