Each successful strike or hit will increase the pH-level of the technique. Extended exposure to it can be fatal for the victim. It's seen that with a singular opponent the technique is quite deadly, allowing Hōsōshi to perform a "face-palm"-move to instantly raise the pH-level of the slime. Potentially, Water Release users could reduce the effects of the technique and eventually wash it off. However, Hōsōshi could counter this — focused on that target — and absorb the water to empower the technique.