Each issue of The Biologic Show contains several short stories and illustrated poems. Many of the pieces deal with disturbing subject matter such as mutilation, incest, and the occult. Issue #0 introduces three of Columbia's recurring characters: the hapless, Koko the Clown-like Seymour Sunshine in the opening story "No Tomorrow If I Must Return", and the sibling duo Pim and Francie in "Tar Frogs". (Both "Tar Frogs" and the aforementioned "The Biologic Show" had originally appeared in the British comics magazine Deadline but were partially redrawn for Columbia's solo book.) Issue #1 is dominated by the 16-page Pim and Francie story "Peloria: Part One", intended as the start of an ongoing serial. It includes another character, Knishkebibble the Monkey-Boy, who reappears in Columbia's later