USS Sans Souci II (SP-301) was an armed motorboat that served in the United States Navy as a patrol vessel from 1917 to 1919. Sans Souci II was built as a civilian motorboat of the same name in 1907 by the shipyard of Frank Tregoning at Seattle, Washington. Following the entry of the United States into World War I, she was enrolled in the Naval Coast Defense Reserve on 15 June 1917. Her owner, D. G. Schmitz of Seattle, delivered her to the U.S. Navy on 9 July 1917 for World War I service as a patrol vessel. She was commissioned as USS Sans Souci II (SP-301) on 1 August 1917 with Chief Boatswain's Mate R. W. Capps, USNRF, in command.