In the IDW Comics Donatello, just like his brothers, is one of the reincarnated sons of Hamato Yoshi, who were murdered in medieval Japan by Shredder. He began his new life in the present as a water turtle hatchling in the laboratory of StockGen Research, Inc., Baxter Stockman's genetics laboratory to serve as a guinea pig for an experiment to create naturally armored super soldiers. Some ninja tried to seize the Turtles and various other research results from the laboratory, including a super solider mutagen. The intervention of his also reborn father, now a lab rat, led to the Turtles and Splinter being wetted with a chemical cocktail that made ​​them ultimately mutants.