In Howling V, Mary Lou Summers was part of a group of random people who all came together in a castle in Budapest that had been closed for 500 years. The host of the gathering, Count Isht Van Bezeli, revealed that they were all descendants of a family that occupied the castle back then and had all committed suicide, while a baby who carried the werewolf curse survived. Because of this, one of the descendants is a werewolf, and he or she had been killing the others one by one.