The 6th Regiment California Volunteer Infantry was an infantry regiment in the Union Army during the American Civil War. It spent its entire term of service in the western United States attached to the Department of the Pacific. The Regiment was organized at Benicia Barracks, San Francisco on February 1, 1863. 6th Regiment mustered out from October 25 to December 20, 1865. The only recorded engagements of the Regiment occurred with the detachment sent to the Humbolt District in 1864, near the end of the Bald Hills War. It had engagements with the Indians in the Skirmish at Booth's Run, May 1 (Company "E") and Kneeland's Prairie May 2 (Company "E"), near Boynton's Prairie May 6 (Company "C") and at Grouse Creek May 23 (Companies "E" and "G").