The 2010 Meineke Car Care Bowl was the ninth edition of the college football bowl game, and was played at Bank of America Stadium in Charlotte, North Carolina. The game started at 12:00 PM US EST on Friday, December 31, 2010 and featured the South Florida Bulls of the Big East Conference against the Clemson Tigers of the ACC. The bowl was telecasted on ESPN and ESPN3. This game was the last game of the series to be called the "Meineke Car Care Bowl", as the bowl organizers terminated their title sponsorship agreement with the parent company of Meineke, effective in 2011.