Spirit's Breath is a synthesized item in Atelier Rorona: The Alchemist of Arland. The recipe book with Spirit's Breath can be found in a chest at the Catacombs. It can be used in battle to reduce the element resistance, defense, speed and attack power of an enemy. Gio may request this as one of his Friend Quests. Esty may request this from the castle as a possible Front Quest. It can be registered at Pamela's shop using wholesale. It is an required ingredient in making the Spirit Necklace and Mystery Potion.