Z43 was a Type 1936B destroyer of the German Kriegsmarine. She was laid down on 1 May 1942 at Deschimag in Bremen, launched on 22 September 1943 and commissioned on 24 March 1944. Her service was with the 6th Destroyer Flotilla in the Baltic Sea under the command of Kapitän zur See Wenniger and later Fregattenkapitän Lampe. She mainly escorted ships, including the "pocket battleship" Admiral Scheer, and participated in a minelaying operation in December 1944, where her sisters Z35 and Z36 were sunk. She was badly damaged by a mine on 10 April 1945, and scuttled on 3 May of that same year.