John I of Antioch was bishop of Antioch A.D. 429-441 and led a group of moderate Eastern bishops during the Nestorian controversy. He is sometimes confused with St. John Chrysostom, who is occasionally also referred to as John of Antioch. Two years later, in 433 John reconciled with Cyril based on the Formula of Reunion, a theological formula devised as a compromise. In the process, John lost many of his own supporters within his patriarchate. Some of his letters are extant.