The USS Defiant (NCC-75633) was originally the USS São Paulo, a Defiant-class escort. The São Paulo (NCC-75633) was launched from the Utopia Planitia Fleet Yards in late 2375 and was sent to Deep Space 9 to replace the USS Defiant, which was destroyed during the Second Battle of Chin'toka. Captain Benjamin Sisko received authorization to re-christen the vessel. The new Defiant took part in the Battle of Cardassia, which ended the Dominion War. (Star Trek: Deep Space Nine, "The Dogs of War", "What You Leave Behind")