Collinson was a devout Christian who was attracted to the devotional and high church aspects of Pre-Raphaelitism. A convert to Catholicism, Collinson reverted to high Anglicanism in order to marry Christina Rossetti, but his conscience forced his return to Catholicism and the break-up of the engagement. When Millais' painting Christ in the House of his Parents was accused of blasphemy, Collinson resigned from the Brotherhood in the belief that it was bringing the Christian religion into disrepute.