Kana: Little Sister (Kana ~Imouto~) is a Visual Novel depicting the story of 15-year-old Kana, a girl who suffers from a chronic life-threatening disease and her older brother, Takamichi (Taka), who supports her and cares for her. The game deals with the relationship between both siblings, which gets more and more intense as time progresses. There is a clear incestuous element later, but which goes far beyond mere physical attraction. An English version of the game was released by G-Collections in 2002, with the erotic content uncensored.