[Source] The Senex-Juvex was a region on the edge of the Mid Rim of the galaxy that comprised the Senex sector and the Juvex sector. Though the region was nominally split into the two sectors, in practice the Senex-Juvex formed a single cultural region, ruled by wealthy Human noble houses that rejected centralized government and supported themselves through an active slave trade. Formed by a group of Core Worlds nobles led by Thull Vandron around 1000 BBY, the Senex-Juvex fiercely guarded its independence and only joined the Galactic Republic shortly before the Clone Wars.
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