STS-42 was a Space Shuttle Discovery mission with the Spacelab module. Liftoff was originally scheduled for 8:45 EST (13:45 UTC) 22 January 1992, but the launch was delayed due to weather constraints. Discovery successfully lifted off an hour later at 9:52 EST (14:52 UTC). The main goal of the mission was to study the effects of microgravity on a variety of organisms. The shuttle landed at 8:07 PST (16:07 UTC) on 30 January 1992 on Runway 22, Edwards Air Force Base, California. STS-42 was the first of two flights in 1992 of Discovery, the second of which occurred during STS-53, which launched on 2 December 1992. The mission was also the last mission of the Space Shuttle Discovery to have a seven-member crew until STS-82, which was launched on 11 February 1997.