Atelopus arsyecue is a species of toad in the Bufonidae family. It is endemic to the Sierra Nevada de Santa Marta, Colombia. Its natural habitats are sub-Andean and Andean forests, sub-páramo and páramo at 2,000–3,500 m (6,600–11,500 ft) above sea level. Reproduction takes place in fast-flowing rivers. It is threatened by chytridiomycosis and habitat loss.