Due to the player using Eleanor, he or she will have access to the newly-introduced Big Sister weapons, as well some Big Daddy weapons from BioShock 2. The player an also do a hard melee attack, while not dealing the same amount of damage that in BioShock 2, it's much faster. Every weapons now has 4 kinds of Ammunition, the fourth being accessed by clicking the left stick.
| Graph IRI | Count |
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| http://dbkwik.webdatacommons.org | 18 |